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Acute inflammation is characterized by its rapid onset and brief duration. There’s also the possibility of a chronic form, which shows up gradually and lasts for a long time. Many serious health problems, including autoimmune illnesses, can develop from it.

In this post, we will examine the signs and possible triggers for chronic inflammation.

First of All, What Is Chronic Inflammation?

Inflammation is your body’s defense mechanism against outside invaders like germs, viruses, injuries, and other potentially hazardous things. It can shut off harmful stimuli and kick off the body’s natural healing process after an injury. When your body detects anything it considers harmful, it responds with a burst of acute inflammation.

When the underlying cause of the inflammation is addressed, like an illness or injury, the inflammatory response normally subsides. However, there are occasions when the body is unable to treat inflammation on its own. If this happens, inflammation in the body may persist for a long time.

When inflammation persists for a long time, it may spread throughout the body and harm multiple organs and tissues.

The Difference between Acute and Chronic Inflammation

When an infection or tissue injury, such as a fractured bone, occurs suddenly, the body’s immune system responds with acute inflammation. White blood cells and macrophages are sent to the part of the body that has been injured, triggering acute inflammation.

In contrast, if acute inflammation does not subside, it might progress into chronic inflammation.

Whenever the body’s inflammatory response to tissue injury or a perceived threat is allowed to persist, a condition known as chronic inflammation results. Even if the danger has passed, this may still occur.

Whenever this occurs, the inflammation that was once a short-term response may progress into a more long-term chronic condition.

The Different Signs of Chronic Inflammation

The location of the inflammation in the body may play a role in the manifestation of chronic inflammation symptoms. According to a study scheduled for publication in 2022, there is a robust and nuanced relationship between chronic inflammation and numerous adverse impacts on physical and mental health.

Some common symptoms of chronic inflammation may include:

  • Discomfort or pain felt throughout the body
  • Discomfort in the joints
  • Changes in body mass or appetite disturbances, or sleeplessness
  • Chronic or recurrent infections
  • Mental health issues, including depression and anxiety, that cause chronic fatigue
  • Illnesses of the digestive tract, such as heartburn, bloating, or bowel irregularity

Even though the signs of acute inflammation are identical, they usually only persist for a few days. Chronic inflammation may be the cause of your symptoms if they return or worsen after a few weeks of treatment.

The Possible Causes of Chronic Inflammation

Several factors can contribute to chronic inflammation, such as:

1. Illness or Infection That Has Not Been Treated

What this term describes is a situation in which the body suffers from an injury or infection that its immune system is unable to fully treat. Over time, microorganisms that infect a host may develop resistance to the immune system’s countermeasures.

2. Constant, Low-Level Exposure

Low-level exposure to an irritant or foreign chemical that the body cannot remove can cause inflammation. Substances or chemicals that a person has inhaled over time are good examples.

3. Substances Causing Cellular Stress or Dysfunction

The term “oxidative stress” is used to describe the buildup of harmful molecules in the body, such as “free radicals,” “uric acid,” and so on. Consequently, this may cause irritation.

4. Repeated Episodes of Acute Inflammation

A chronic inflammatory response can develop after repeated episodes of acute inflammation.

5. Autoimmune Diseases

In autoimmune disorders, the body’s immune system mistakenly targets healthy tissue. Celiac disease, diabetes, rheumatoid arthritis, and systemic lupus erythematosus are all examples of autoimmune illnesses.

6. Cell Impairments

Defects or impairments in the cells responsible for regulating inflammation can cause inflammation to persist or reoccur. Some diseases, such as familial Mediterranean fever, can cause this.


Chronic inflammation is a condition in which the body’s inflammatory response is continuously activated. This can lead to a range of symptoms, including fatigue, joint pain, and digestive issues. While there is no cure for chronic inflammation, there are treatments that can help manage the symptoms and improve quality of life.

Be sure to consult your doctor if ever you experience any of its recurring symptoms.

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